Glaucoma filtering surgery is unusual in that its goal is the creation and maintenance of a non healing fistula between two anatomic spaces that are normally not connected [1].
Fibroblasts, connective tissue elements, cytokines, aqueous humor and the surrounding vascular supply all influence what happens to a bleb over a long period of time.
The enemy of drainage procedure is excessive scarring [2].
Long-term studies showed a loss of intraocular pressure (IOP) control in a significant proportion of eyes with an initially successful trabeculectomy [2,3]. So follow up of glaucoma patients after surgery is mandatory as significant proportion develop bleb failure.
Revision of guarded filtration procedures was reported as early as 1941 by Ferrer [4]. Needling as currently performed was described by Pederson and Smith [5]. The combination of needling with antimetabolites (mitomycin C and 5FU) greatly improve the outcome of needling and enhance bleb survival.
Keywords: Antimetabolites; Needling; Mitomycin C; 5-Fluorouracil
Published on: Dec 12, 2014 Pages: 7-9
Full Text PDF
Full Text HTML
DOI: 10.17352/2455-1414.000008
CrossMark
Publons
Harvard Library HOLLIS
Search IT
Semantic Scholar
Get Citation
Base Search
Scilit
OAI-PMH
ResearchGate
Academic Microsoft
GrowKudos
Universite de Paris
UW Libraries
SJSU King Library
SJSU King Library
NUS Library
McGill
DET KGL BIBLiOTEK
JCU Discovery
Universidad De Lima
WorldCat
VU on WorldCat
PTZ: We're glad you're here. Please click "create a new query" if you are a new visitor to our website and need further information from us.
If you are already a member of our network and need to keep track of any developments regarding a question you have already submitted, click "take me to my Query."