Chloramphenicol is a widely used topical ointment applied routinely for ocular and periorbital infections due to its wide spectrum of anti-bacterial activity. Local delayed hypersensitivity reaction to chloramphenicol is a well reported but uncommon adverse effect, and has been reported to be mismanaged initially as an infective cellulitis [1]. Hereby, we are reporting a case of local hypersensitivity reaction to chloramphenicol after ocular use for adenexal infection, which was diagnosed with high index of suspicion without any clinical test, and was managed timely and successfully.
Case History
A 38-year-old man presented to out-patient department with painless swelling around both eyes of 24 hours duration. Onset of swelling was sudden, and started around 48 hours after application of chloramphenicol ointment for stye. There was no history of fever and any drug allergy. Patient also gave the history of recurrent stye in both eyes and the chloramphenicol ointment was prescribed for the same
by a general physician in a government hospital about two months back. Patient used the same ointment pack, which was opened about two months back.
Keywords: Chloramphenicol; Hypersensitivity; Periorbital infection
Published on: Sep 15, 2014 Pages: 1-2
Full Text PDF
Full Text HTML
DOI: 10.17352/2455-1414.000006
CrossMark
Publons
Harvard Library HOLLIS
Search IT
Semantic Scholar
Get Citation
Base Search
Scilit
OAI-PMH
ResearchGate
Academic Microsoft
GrowKudos
Universite de Paris
UW Libraries
SJSU King Library
SJSU King Library
NUS Library
McGill
DET KGL BIBLiOTEK
JCU Discovery
Universidad De Lima
WorldCat
VU on WorldCat
PTZ: We're glad you're here. Please click "create a new query" if you are a new visitor to our website and need further information from us.
If you are already a member of our network and need to keep track of any developments regarding a question you have already submitted, click "take me to my Query."