Invasive yeast infection in patient with Acute pancreatitis

Jana Simonova, Lukas Cuchrac, Jozef Firment, Viktoria Takacova, Ladislav Vasko, Janka Vaskova*

The incidence of invasive yeast infections is rising in patients hospitalised in intensive care. Their early

diagnosis is problematic, although predictive models (Pitt’s colonization index, Leon score and others)

can be helpful when deciding to initiate treatment. The incidence of candidiasis signifi cantly increases

the mortality of patients, although the timely commencement of antimycotic therapy is a key factor

in increasing their survival. In the present patient, antibiotic treatment with carbapenem was initiated

after CT verifi cation of necrosis with formation of abscesses and the onset of infl ammatory parameters.

After surgical review, septic shock developed with multi-organ failure. Microbiological examinations of

biological materials also revealed non-C. albicans yeast was present in haemocultures, so echinocandin

and anidulafungin were included in the treatment. C. parapsilosis persisted in haemocultures, while

negative haemoculture was obtained 14 days after the inclusion of liposomal amphotericin B.

Keywords: Pancreatitis; Intra-abdominal infections; Antimycotic treatment

Published on: Nov 29, 2017 Pages: 6-10

Full Text PDF Full Text HTML DOI: 10.17352/2455-8702.000034
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