Vitamin D presents interesting pleiotropic effects for the CKD patient (effect and anti-inflammatory properties). Patients with chronic kidney disease (CKD) have impaired endothelial function and the Vitamin D and its analogs may play a role in regulation of endothelial function and inflammation. Therefore, it is increasingly observed that CKD is characterized by a state of chronic inflammation that appears to be linked to oxidative stress, endothelial dysfunction and vascular calcification. Previous studies have shown that vitamin D administration in chronic renal failure patients produces therapeutic effects suggesting an inverse relationship between the presence of 25-hydroxyvitamin D [25 (OH) D] and inflammatory biomarkers. It is emphasized so the importance of proper maintenance of the vitamin D status, since it plays an important role in the management of inflammation and immunity, contributing to the reduction of morbidity and mortality in patients with CKD. In addition there is cumulative evidence showing the low level of vitamin D associations with the development and progression of chronic kidney disease, cardiovascular complications and high mortality.
Keywords:
Published on: Feb 25, 2016 Pages: 8-10
Full Text PDF
Full Text HTML
DOI: 10.17352/acn.000007
CrossMark
Publons
Harvard Library HOLLIS
Search IT
Semantic Scholar
Get Citation
Base Search
Scilit
OAI-PMH
ResearchGate
Academic Microsoft
GrowKudos
Universite de Paris
UW Libraries
SJSU King Library
SJSU King Library
NUS Library
McGill
DET KGL BIBLiOTEK
JCU Discovery
Universidad De Lima
WorldCat
VU on WorldCat
PTZ: We're glad you're here. Please click "create a new query" if you are a new visitor to our website and need further information from us.
If you are already a member of our network and need to keep track of any developments regarding a question you have already submitted, click "take me to my Query."