Randomized Vitamin D Supplementation in Vitamin D Deficient Obese Children from West Virginia

Yoram Elitsur* and Deborah L Preston

Objective: Vitamin D (Vit D) defi ciency is a very common problem in obese children, but clinical guidelines for maintenance or treatment have not been published for this population. The aim was to assess the benefi t of 2 months Vit D supplementation given to defi cient obese children from WV.

Design: Vit D defi cient obese children were prospectively recruited. Exclusion criteria included <8 years, and medical conditions that may affect Vit D homeostasis. Participants were randomized into two  supplement groups: 5,000IU/day (Group A) or 50,000IU/week (Group B). Serum 25(OH)D levels were measured at baseline and post-treatment.

Results: Sixty obese children were screened of whom 39 (65%) were defi cient (<20ng/ml). Of the 39  recruited, 26 completed the study. The mean serum 25(OH)D after 2 months treatment were signifi cantly

higher in Group B (p= 0.02), but most reached normal levels (>30ng/ml). 

Conclusions: Two months Vit D supplementation (5000IU/day or 50,000IU/week) was suffi cient to normalize 25(OH)D levels in Vit D defi cient obese West Virginian children.

Keywords: Vit D deficiency; Children; Obesity

Published on: Dec 8, 2016 Pages: 65-68

Full Text PDF Full Text HTML DOI: 10.17352/2455-2283.000024
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